Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.52 |
| ▸ | HTR2C | P28335 | 6/20 | 0.52 |
| ▸ | HTR2B | P41595 | 6/20 | 0.52 |
| ▸ | HRH2 | P25021 | 9/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796371 | 0.84 | HTR2A (0.49) | HTR2AHTR2CHTR2BHRH2FOLH1 | |
| SCHEMBL5343753 | 0.81 | HRH2 (0.58) | HTR2AHTR2CHTR2BHRH2POLB | |
| SCHEMBL6796373 | 0.79 | POLB (0.49) | HTR2AHTR2CHTR2BHRH2POLB | |
| SCHEMBL5345903 | 0.78 | HRH2 (0.60) | HTR2AHTR2CHTR2BHRH2POLB | |
| SCHEMBL5341713 | 0.74 | HRH2 (0.73) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL5358193 | 0.71 | HTR2A (0.77) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL5358714 | 0.71 | HRH2 (0.80) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL5345507 | 0.70 | HRH2 (0.64) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL4058074 | 0.70 | HRH2 (0.65) | HTR2AHTR2CHTR2BHRH2 | |
| SCHEMBL7094542 | 0.70 | HRH2 (0.60) | HTR2AHTR2CHTR2BHRH2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116471-A1 | Indolylpiperidine derivatives as antihistaminic aand antiallergic agents | ALMIRALL PRODESFARMA S.A. (ES) | 2004-06-17 | — | — | US | disclosed |