SCHEMBL6796718

SCHEMBL6796718

CCCN(CCC)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
MAPT P10636 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CRHR1 P34998 7/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715579 0.90 CYP3A4 (0.30) TDP1CYP3A4TSHRMAPK1MAPT
SCHEMBL5716555 0.89 CYP3A4 (0.31) TDP1CYP3A4TSHRMAPK1CRHR1
SCHEMBL5716286 0.87 DNM1 (0.39) TDP1CYP3A4TSHRMAPK1
SCHEMBL5715545 0.87 DNM1 (0.39) TDP1CYP3A4TSHRMAPK1
SCHEMBL5082545 0.80 DNM1 (0.42) TSHR
SCHEMBL21519592 0.80 DNM1 (0.42) TSHR
SCHEMBL3978473 0.80 DNM1 (0.42) TSHR
SCHEMBL5088802 0.80 DNM1 (0.42) TSHR
SCHEMBL29002046 0.80 DNM1 (0.42) TSHR
SCHEMBL6439463 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed