Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.73 |
| ▸ | RAB9A | P51151 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | NQO2 | P16083 | 2/20 | 0.70 |
| ▸ | DEGS1 | O15121 | 2/20 | 0.68 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | SNCA | P37840 | 2/20 | 0.58 |
| ▸ | TOP1 | P11387 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22067843 | 0.92 | TP53 (0.77) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL8773726 | 0.91 | MEN1 (0.69) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL2063559 | 0.89 | KMT2A (0.77) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18993384 | 0.88 | MEN1 (0.65) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL10804897 | 0.88 | MEN1 (0.81) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22228326 | 0.88 | MEN1 (0.65) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL18027783 | 0.88 | NPC1 (0.71) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL6793906 | 0.87 | MEN1 (0.93) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29800565 | 0.87 | MEN1 (0.93) | TP53NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21707396 | 0.85 | MEN1 (0.89) | TP53NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |
| EP-0700532-B1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | AVENTIS RES & TECH GMBH & CO (DE) | 2000-03-29 | — | — | EP | disclosed |
| US-5744203-A | POLYMER MIXTURES OF POLYURETHANES, POLYESTERS, POLYIMIDES, POLYCARBONATES AND POLYUREAS | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5670084-A | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-23 | — | — | US | disclosed |
| EP-0708149-A1 | Alignment layer material for liquid crystal display devices | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-24 | — | — | EP | disclosed |
| EP-0700532-A1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994028458-A1 | ALIGNMENT LAYER FOR LIQUID CRYSTALS | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-12-08 | — | — | WO | disclosed |