Styrene

Styrene

SCHEMBL679691

C=CC(=C)C.C=CC=CC(=C)C.C=Cc1ccccc1.C=Cc1ccccc1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 3/20 0.50
CYP3A4 P08684 1/20 0.40
TDP1 Q9NUW8 2/20 0.37
TP53 P04637 2/20 0.37
GLA P06280 1/20 0.36
ALOX15 P16050 1/20 0.34
AKR1C3 P42330 1/20 0.32
HDAC8 Q9BY41 3/20 0.32
TGM2 P21980 1/20 0.32
MAOB P27338 2/20 0.31
AKT1 P31749 1/20 0.31
HDAC3 O15379 1/20 0.31
TNKS O95271 1/20 0.31
HDAC4 P56524 1/20 0.31
HDAC1 Q13547 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
HDAC7 Q8WUI4 1/20 0.31
HDAC2 Q92769 1/20 0.31
HDAC10 Q969S8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL374493 0.96 ALDH1A1 (0.54) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL1768760 0.96 ALDH1A1 (0.54) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL28398301 0.87 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL2209240 0.87 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL28744480 0.87 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL6526981 0.87 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL3311197 0.87 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL27291 0.87 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL1616325 0.87 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1TP53
Styrene SCHEMBL35198 0.87 ALDH1A1 (0.61) ALDH1A1TSHRCYP3A4TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4299294-A2 PROCESS FOR THE PRODUCTION OF OBJECTS USING ADDITIVE MANUFACTURING Eastman Chemical Company (US) 2024-01-03 EP disclosed
EP-3377320-B1 COMPOSITIONS FOR THE PRODUCTION OF OBJECTS USING ADDITIVE MANUFACTURING EASTMAN CHEM CO (US) 2023-11-15 EP disclosed
EP-3377320-A1 COMPOSITIONS FOR THE PRODUCTION OF OBJECTS USING ADDITIVE MANUFACTURING Eastman Chemical Company (US) 2018-09-26 EP disclosed
US-20170145155-A1 COMPOSITIONS FOR THE PRODUCTION OF OBJECTS USING ADDITIVE MANUFACTURING EASTMAN CHEMICAL COMPANY (US) 2017-05-25 US disclosed
US-8178647-B2 Copolyester ether elastomer compositions and methods of making copolyester ether elastomer compositions EASTMAN CHEMICAL COMPANY (US) 2012-05-15 US disclosed
US-20120053568-A1 COPOLYESTER ETHER ELASTOMER COMPOSITIONS AND METHODS OF MAKING COPOLYESTER ETHER ELASTOMER COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2012-03-01 US disclosed
US-20120048380-A1 Tubing and Methods of Making Tubing Comprising Copolyester Ether Elastomer Compositions EASTMAN CHEMICAL COMPANY (US) 2012-03-01 US disclosed
US-20110047819-A1 SOFT, SHOCK-DAMPING THERMOPLASTIC ELASTOMERS POLYONE CORPORATION (US) 2011-03-03 US disclosed
WO-2009032669-A3 SOFT, SHOCK-DAMPING THERMOPLASTIC ELASTOMERS POLYONE CORP (US) 2009-04-30 WO disclosed
WO-2009032669-A2 SOFT, SHOCK-DAMPING THERMOPLASTIC ELASTOMERS POLYONE CORPORATION (US) 2009-03-12 WO disclosed