SCHEMBL6797154

SCHEMBL6797154

CCCN(CC)c1cc(F)c(F)c(C(F)(F)F)c1F

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.34
MAPK1 P28482 2/20 0.34
TSHR P16473 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
AR P10275 2/20 0.32
MAPT P10636 1/20 0.31
IGLV6-57 P01721 1/20 0.31
CRHR1 P34998 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5716043 0.90 RIPK1 (0.31)
SCHEMBL6785586 0.89 CYP3A4 (0.33) CYP3A4MAPK1TSHRTDP1AR
SCHEMBL5716134 0.88 CYP3A4 (0.36) CYP3A4MAPK1TDP1MAPTCRHR1
SCHEMBL5716392 0.88 CYP3A4 (0.35) CYP3A4MAPK1TSHRTDP1AR
SCHEMBL5716037 0.88 IGLV6-57 (0.30) CYP3A4MAPK1TSHRTDP1IGLV6-57
SCHEMBL6791971 0.85
SCHEMBL5715588 0.85 CYP3A4 (0.32) CYP3A4MAPK1TSHRTDP1MAPT
SCHEMBL6796191 0.84 IGLV6-57 (0.35) IGLV6-57
SCHEMBL5715922 0.82
SCHEMBL5716306 0.81 CYP3A4 (0.30) CYP3A4MAPK1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed