SCHEMBL6797667

SCHEMBL6797667

SCCc1cc[c]cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2809595 0.82
SCHEMBL27625038 0.78
SCHEMBL7370699 0.78
SCHEMBL3045246 0.78
SCHEMBL533253 0.78
SCHEMBL7367223 0.78 TAAR1 (0.36)
SCHEMBL15013570 0.75
SCHEMBL533287 0.75 KCNH2 (0.38)
SCHEMBL28315278 0.75 NOS3 (0.39)
SCHEMBL533691 0.74 KCNH2 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680314-B2 USEFUL FOR THE TREATMENT OF DISEASES INVOLVING THE CHOLINERGIC SYSTEM OF THE CENTRAL NERVOUS SYSTEM, PAIN, INFLAMMATORY DISEASES, DISEASES CAUSED BY SMOOTH MUSCLE CONTRACTIONS, LEARNING DEFICIT, COGNITION DEFICIT, ATTENTION DEFICIT NEUROSEARCH A/S (DK) 2004-01-20 US claimed
CN-1124266-C Azacyclooctane and heptane derivatives, their preparation and usein therapy NEUROSEACH AS (DK) 2003-10-15 CN claimed
EP-0984943-B1 AZACYCLOOCTANE AND HEPTANE DERIVATIVES, THEIR PREPARATION AND USEIN THERAPY NEUROSEARCH AS (DK) 2002-12-11 EP claimed
US-20020169156-A1 Azacyclooctane and heptane derivatives, their preparation and use in therapy NEUROSEARCH A/S 2002-11-14 US claimed
US-6420395-B1 DISORDERS OR DISEASES INVOLVING THE CHOLINERGIC SYSTEM OF THE CENTRAL NERVOUS SYSTEM, PAIN, INFLAMMATORY DISEASES, DISEASES CAUSED BY SMOOTH MUSCLE CONTRACTIONS AND AS ASSISTANCE IN THE CESSATION OF CHEMICAL SUBSTANCE ABUSE. NEUROSEARCH A/S (DK) 2002-07-16 US claimed
CN-1257485-A Azacyclooctane and heptane derivatives, their preparation and usein therapy NEUROSEACH A S (DK) 2000-06-21 CN claimed
EP-0984943-A1 AZACYCLOOCTANE AND HEPTANE DERIVATIVES, THEIR PREPARATION AND USEIN THERAPY NEUROSEARCH A/S (DK) 2000-03-15 EP claimed
WO-1998054152-A1 AZACYCLOOCTANE AND HEPTANE DERIVATIVES, THEIR PREPARATION AND USEIN THERAPY NEUROSEARCH A/S (DK) 1998-12-03 WO claimed
US-6680314-B2 USEFUL FOR THE TREATMENT OF DISEASES INVOLVING THE CHOLINERGIC SYSTEM OF THE CENTRAL NERVOUS SYSTEM, PAIN, INFLAMMATORY DISEASES, DISEASES CAUSED BY SMOOTH MUSCLE CONTRACTIONS, LEARNING DEFICIT, COGNITION DEFICIT, ATTENTION DEFICIT NEUROSEARCH A/S (DK) 2004-01-20 US disclosed
CN-1124266-C Azacyclooctane and heptane derivatives, their preparation and usein therapy NEUROSEACH AS (DK) 2003-10-15 CN disclosed
EP-0984943-B1 AZACYCLOOCTANE AND HEPTANE DERIVATIVES, THEIR PREPARATION AND USEIN THERAPY NEUROSEARCH AS (DK) 2002-12-11 EP disclosed
US-20020169156-A1 Azacyclooctane and heptane derivatives, their preparation and use in therapy NEUROSEARCH A/S 2002-11-14 US disclosed
US-6420395-B1 DISORDERS OR DISEASES INVOLVING THE CHOLINERGIC SYSTEM OF THE CENTRAL NERVOUS SYSTEM, PAIN, INFLAMMATORY DISEASES, DISEASES CAUSED BY SMOOTH MUSCLE CONTRACTIONS AND AS ASSISTANCE IN THE CESSATION OF CHEMICAL SUBSTANCE ABUSE. NEUROSEARCH A/S (DK) 2002-07-16 US disclosed
CN-1257485-A Azacyclooctane and heptane derivatives, their preparation and usein therapy NEUROSEACH A S (DK) 2000-06-21 CN disclosed