Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6751215 | 0.95 | KDR (0.39) | KDRFLT1 | |
| SCHEMBL6749189 | 0.92 | KDR (0.39) | KDRFLT1 | |
| SCHEMBL6751239 | 0.86 | KDR (0.39) | KDRFLT1 | |
| SCHEMBL6683408 | 0.85 | KDR (0.36) | KDRFLT1 | |
| SCHEMBL6683410 | 0.80 | KDR (0.37) | KDRFLT1 | |
| SCHEMBL6751012 | 0.80 | SCN9A (0.40) | KDRFLT1 | |
| SCHEMBL6751946 | 0.80 | RAB9A (0.41) | KDRFLT1 | |
| SCHEMBL6752000 | 0.80 | RAB9A (0.41) | KDRFLT1 | |
| SCHEMBL6751950 | 0.80 | RAB9A (0.41) | KDRFLT1 | |
| SCHEMBL6747209 | 0.79 | KDR (0.49) | KDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833456-B2 | Heterocyclic sulfides such as 5-(2-(2R-Hydroxymethyl-pyrrolidine-1-carbonyl)-thieno(3,2-b)pyridin-7 -ylamino)-2-methyl-indole-1-carboxylic acid methylamide, used as angiogenesis inhibitors | AGOURON PHARMACEUTICALS, INC. | 2004-12-21 | — | — | US | disclosed |