Biphenyl

Biphenyl

SCHEMBL6798167

CCCCCCCCCNCC.CCCCCCCCCNCC.CCCCCCCCCNCC.Fc1ccc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1ccc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1ccc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1ccc(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.OB(O)O.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.39
SIGMAR1 Q99720 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
PTGS2 P35354 4/20 0.34
FAAH O00519 2/20 0.34
SOAT1 P35610 2/20 0.33
NAAA Q02083 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL6470283 0.90 EPHX2 (0.39) EPHX2SIGMAR1PTGS2FAAHSOAT1
SCHEMBL5716247 0.83 EPHX2 (0.46) EPHX2SIGMAR1MEN1KMT2ASMN1; SMN2
SCHEMBL5716271 0.83 TSHR (0.44) EPHX2MEN1KMT2ASMN1; SMN2HRH4
Boric Acid SCHEMBL6799213 0.81 EPHX2 (0.32) EPHX2
SCHEMBL5716446 0.81 EPHX2 (0.45) EPHX2SIGMAR1MEN1KMT2ASMN1; SMN2
Biphenyl SCHEMBL6791283 0.81 EPHX2 (0.31) EPHX2
SCHEMBL5715671 0.80 EPHX2 (0.44) EPHX2SIGMAR1MEN1KMT2ASMN1; SMN2
SCHEMBL5715753 0.79 EPHX2 (0.43) EPHX2SIGMAR1MEN1KMT2ASMN1; SMN2
SCHEMBL5715754 0.78 SMN1; SMN2 (0.46) EPHX2SIGMAR1MEN1KMT2ASMN1; SMN2
SCHEMBL5716103 0.78 SMN1; SMN2 (0.46) EPHX2SIGMAR1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed