Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6790215 | 0.90 | PARP1 (0.54) | PARP1SMN1; SMN2MAPTPDE10AALDH1A1 | |
| SCHEMBL6798298 | 0.88 | PARP1 (0.60) | PARP1MAPTPDE10AALDH1A1KMT2A | |
| SCHEMBL6791743 | 0.87 | PARP1 (0.54) | PARP1SMN1; SMN2MAPTPDE10AALDH1A1 | |
| SCHEMBL6802146 | 0.84 | PARP1 (0.55) | PARP1MAPTPDE10AKMT2APARP2 | |
| SCHEMBL6795593 | 0.84 | PARP1 (0.64) | PARP1SMN1; SMN2PDE10AALDH1A1KMT2A | |
| SCHEMBL6795464 | 0.83 | PARP1 (0.63) | PARP1SMN1; SMN2PDE10AALDH1A1KMT2A | |
| SCHEMBL6795780 | 0.81 | PARP1 (0.61) | PARP1SMN1; SMN2PDE10AALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL6789135 | 0.81 | PDE10A (0.70) | PARP1PDE10AALDH1A1KMT2APARP2 | |
| SCHEMBL4602305 | 0.77 | ALDH1A1 (0.65) | PARP1SMN1; SMN2MAPTPDE10AALDH1A1 | |
| SCHEMBL30176852 | 0.76 | PARP1 (0.73) | PARP1PDE10AALDH1A1KMT2APARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040077667-A1 | Quinazolinone derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077667-A1 | Quinazolinone derivatives | PARP1, PARP9, PARP2 | PARP1 1/4885SMN1; SMN2 3583/4885MAPT 3330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.