Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 5/20 | 0.52 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798388 | 1.00 | ATM (0.53) | ATMAPPHCAR2L3MBTL1TSHR | |
| SCHEMBL27224520 | 0.94 | APP (0.54) | ATMAPPHCAR2TSHRCYP1A2 | |
| SCHEMBL22881952 | 0.91 | APP (0.50) | ATMAPPHCAR2KEAP1NFE2L2 | |
| SCHEMBL22881953 | 0.86 | HSP90AA1 (0.44) | ATMKEAP1NFE2L2HSP90AA1 | |
| SCHEMBL29550384 | 0.85 | CA12 (0.51) | ATMKEAP1NFE2L2HSP90AA1 | |
| SCHEMBL2302128 | 0.85 | CA12 (0.51) | ATMKEAP1NFE2L2HSP90AA1 | |
| SCHEMBL2302901 | 0.85 | CA12 (0.51) | ATMKEAP1NFE2L2HSP90AA1 | |
| SCHEMBL22881937 | 0.85 | HRH1 (0.43) | L3MBTL1TDP1KEAP1NFE2L2CYP1A2 | |
| Hydrochloric Acid SCHEMBL28537989 | 0.84 | HSP90AA1 (0.43) | ATMKEAP1NFE2L2HSP90AA1 | |
| Hydrochloric Acid SCHEMBL29992002 | 0.84 | HSP90AA1 (0.43) | ATMKEAP1NFE2L2HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025080946-A2 | RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2025-04-17 | — | — | WO | disclosed |
| US-6784295-B2 | CARRIED OUT IN THE PRESENCE OF AN INORGANIC BASE OR ORGANIC NITROGEN BASE AND A PALLADIUM COMPLEX CATALYST CONTAINING SECONDARY MONOPHOSPHINES WITH ALIPHATIC, BRANCHED OR CYCLIC SUBSTITUENTS AS LIGANDS | SOLVIAS AG (CH) | 2004-08-31 | — | — | US | disclosed |
| EP-1132361-B1 | Coupling of nucleophiles, vinyl compounds or CO with water, alcohols or amines to organic compounds | SOLVIAS AG (CH) | 2003-05-14 | — | — | EP | disclosed |