Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EIF4E | P06730 | 3/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | PPOX | P50336 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798068 | 0.84 | P2RX1 (0.46) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL593074 | 0.84 | TSHR (0.60) | MAPTTSHRMEN1KMT2ATDP1 | |
| SCHEMBL9189144 | 0.81 | TSHR (0.54) | MAPTTSHRMEN1KMT2ATDP1 | |
| SCHEMBL6800263 | 0.81 | TSHR (0.62) | MAPTLMNATSHREIF4EMEN1 | |
| SCHEMBL8473657 | 0.81 | TSHR (0.54) | MAPTTSHREIF4EMEN1KMT2A | |
| SCHEMBL8610738 | 0.80 | TSHR (0.68) | MAPTTSHRMEN1KMT2ATDP1 | |
| SCHEMBL29471725 | 0.80 | TSHR (0.68) | MAPTTSHRMEN1KMT2ATDP1 | |
| SCHEMBL6704877 | 0.78 | TTR (0.53) | P2RX1TTRKDM4EALDH1A1FABP4 | |
| SCHEMBL6224986 | 0.77 | AKR1B1 (0.51) | AKR1B1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29979402 | 0.77 | SMO (0.50) | KDM4EALDH1A1FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | AKR1B1 181/4885AKR1C4 596/4885AKR1C3 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.