Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785059 | 0.82 | HRH4 (0.43) | LMNACYP1A2SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL3238454 | 0.77 | CNR2 (0.50) | CNR2LMNACYP1A2SMN1; SMN2CYP3A4 | |
| SCHEMBL3247766 | 0.77 | GALR2 (0.50) | CNR2LMNANAPEPLDMAPT | |
| SCHEMBL6790023 | 0.76 | MAPT (0.40) | LMNACYP1A2SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL6789606 | 0.73 | CYBB (0.49) | LMNACYP1A2SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL6788466 | 0.73 | HRH4 (0.44) | LMNACYP1A2SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL3236690 | 0.72 | ROCK2 (0.53) | LMNACYP1A2SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL6791293 | 0.71 | MAPT (0.53) | LMNACYP2C9MAPTNPSR1HTR2A | |
| SCHEMBL6788991 | 0.70 | TDP1 (0.44) | LMNACYP1A2SMN1; SMN2CYP3A4CYP2C9 | |
| SCHEMBL6789794 | 0.70 | SCN9A (0.44) | LMNACYP1A2SMN1; SMN2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040127502-A1 | Use of GAL3 antagonist for treatment of depression | SYNAPTIC PHARMACEUTICAL CORPORATION | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127502-A1 | Use of GAL3 antagonist for treatment of depression | GALR3, GALR2, GALR1 | CNR2 113/4885LMNA 2170/4885CYP1A2 2605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.