Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.45 |
| ▸ | LPL | P06858 | 2/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.44 |
| ▸ | GAK | O14976 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804619 | 0.79 | NT5E (0.69) | NT5EGAKKDRHPGD | |
| SCHEMBL6799283 | 0.77 | NT5E (0.47) | NT5EGAKKDRKCNH2 | |
| SCHEMBL6797821 | 0.75 | NT5E (0.47) | NT5EGAKKDR | |
| SCHEMBL7417006 | 0.73 | NT5E (0.45) | NT5EGAKKDRHPGD | |
| SCHEMBL6796978 | 0.72 | NT5E (0.45) | NT5EGAKKDRHPGD | |
| SCHEMBL6804409 | 0.71 | NT5E (0.44) | NT5EGAKKDRHPGD | |
| SCHEMBL6807826 | 0.71 | NT5E (0.44) | NT5EGAKKDRHPGD | |
| SCHEMBL6803894 | 0.71 | NT5E (0.44) | NT5EGAKKDRHPGD | |
| SCHEMBL6799281 | 0.71 | NT5E (0.43) | NT5EGAKKDRHPGD | |
| SCHEMBL6803865 | 0.69 | NT5E (0.42) | NT5EGAKKDRHPGDIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723735-B1 | TREATMENT OR PREVENTION OF ANXIETY | MERCK SHARP & DOHME LTD. | 2004-04-20 | — | — | US | disclosed |
| EP-1214319-B1 | IMIDAZO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME (GB) | 2003-11-26 | — | — | EP | disclosed |