Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798958 | 0.74 | PANK3 (0.36) | — | |
| SCHEMBL20141404 | 0.74 | FPR2 (0.48) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21812384 | 0.71 | MKNK1 (0.44) | PDE10A | |
| SCHEMBL14663800 | 0.71 | SLC6A2 (0.48) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL15205316 | 0.71 | MKNK1 (0.44) | PDE10A | |
| SCHEMBL10385636 | 0.71 | SLC6A4 (0.66) | CA1CA2CA4CA9SLC6A2 | |
| SCHEMBL24881100 | 0.69 | PDE10A (0.42) | PDE10A | |
| SCHEMBL30112432 | 0.69 | PDE10A (0.42) | PDE10A | |
| SCHEMBL344799 | 0.69 | PDE10A (0.55) | PDE10A | |
| SCHEMBL27865380 | 0.68 | SLC6A4 (0.48) | CA1CA2CA4CA9SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689779-B2 | PYRIDINE OR PYRIMIDINE SUBSTITUTED; ANTIBACTERIAL ACTIVITY; LOW TOXICITY | DONG A PHARM. CO., LTD. (KR) | 2004-02-10 | — | — | US | disclosed |