Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.57 |
| ▸ | GAA | P10253 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 6/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | GLA | P06280 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | FHIT | P49789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6799413 | 0.83 | KDM4E (0.64) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL12987943 | 0.80 | KDM4E (0.65) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL8369419 | 0.77 | KDM4E (0.55) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL11066632 | 0.75 | KDM4E (0.61) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL14756285 | 0.74 | KDM4E (0.62) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL12988158 | 0.72 | KDM4E (0.79) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL6991771 | 0.71 | KDM4E (0.62) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL11193363 | 0.71 | KDM4E (0.68) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL11384270 | 0.70 | SRD5A1 (0.67) | KDM4EKMT2AGAAHPGDHSD17B10 | |
| SCHEMBL8876001 | 0.70 | KDM4E (0.76) | KDM4EKMT2AGAAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6680025-B2 | PREVENTING CARRYOVER CONTAMINATION USING PSORALENS AND ISOPSORALENS | CERUS CORPORATION | 2004-01-20 | — | — | US | disclosed |
| US-20030170141-A1 | Device and method for photoactivation | CERUS CORPORATION (US) | 2003-09-11 | — | — | US | disclosed |
| US-6461567-B1 | FOR CONTROLLING CARRYOVER USING PSORALENS WHICH INTERCALATE BETWEEN BASE PAIRS OF DOUBLE-STRANDED NUCLEIC ACIDS, FORMING COVALENT ADDUCTS TO PYRIMIDINE BASES UPON ABSORPTION OF ULTRAVIOLET LIGHT | CERUS CORPORATION | 2002-10-08 | — | — | US | disclosed |
| US-20020044885-A1 | Device and method for photoactivation | HEARST DAVID PAUL (US) | 2002-04-18 | — | — | US | disclosed |
| US-6258319-B1 | FOR PHOTOACTIVATING NEW AND KNOWN COMPOUNDS; FOR BINDING COMPOUNDS TO NUCLEIC ACID | CERUS CORPORATION | 2001-07-10 | — | — | US | disclosed |
| EP-0497921-B1 | METHOD FOR INHIBITING ENZYMATIC SYNTHESIS OF NUCLEIC ACIDS USING ISOPSORALENS | ISAACS STEPHEN T (US) | 1999-05-19 | — | — | EP | disclosed |
| EP-0890363-A2 | A device for nucleic acid sterilization | ISAACS, Stephen T. (US) | 1999-01-13 | — | — | EP | disclosed |
| US-5854967-A | Device and method for photoactivation | CERUS CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5683661-A | ELECTROMAGNETIC RADIATION, SUPPORTING A SAMPLE IN OPAQUE HOUSING | CERUS CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5503721-A | IRRADIATING SAMPLE VESSEL WHILE HOLDING IN FIXED POSITION | HRI RESEARCH, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| US-5221608-A | Adding a polymerase and an isopsoralen compound to a mixture of nucleic acid and amplification reagents, and exposing to ultraviolet radiation to form isopsoralen monoadduct which inhibits polymerase | STERITECH, INC. | 1993-06-22 | — | — | US | disclosed |
| US-5184020-A | For treating photoreactive compounds | STERITECH, INC. | 1993-02-02 | — | — | US | disclosed |
| US-5139940-A | Isopsoralen derives; complex with nucleic acids | STERITECH, INC. | 1992-08-18 | — | — | US | disclosed |