Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31551042 | 1.00 | CYP19A1 (0.55) | CYP19A1SMN1; SMN2CASP6CASP3SENP8 | |
| SCHEMBL27654823 | 0.98 | CYP19A1 (0.53) | CYP19A1SMN1; SMN2CASP6CASP3SENP8 | |
| Hydrochloric Acid SCHEMBL15621988 | 0.98 | CYP19A1 (0.53) | CYP19A1SMN1; SMN2CASP6CASP3SENP8 | |
| SCHEMBL30958362 | 0.87 | SMN1; SMN2 (0.57) | CYP19A1SMN1; SMN2CASP6CASP3SENP8 | |
| SCHEMBL21823234 | 0.87 | SMN1; SMN2 (0.57) | CYP19A1SMN1; SMN2CASP6CASP3SENP8 | |
| SCHEMBL23263176 | 0.82 | CASP6 (0.46) | CYP19A1SMN1; SMN2CASP6MAPK1IDO1 | |
| SCHEMBL28926745 | 0.82 | CYP19A1 (0.49) | CYP19A1SMN1; SMN2CASP6CASP3SENP8 | |
| SCHEMBL29376972 | 0.81 | SMN1; SMN2 (0.50) | CYP19A1SMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL45750 | 0.81 | SMN1; SMN2 (0.50) | CYP19A1SMN1; SMN2CASP3SENP8SENP7 | |
| SCHEMBL10599951 | 0.81 | KDM4E (0.45) | SMN1; SMN2CASP6ALDH1A1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 162 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3773552-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC Therapeutics, Inc. (US) | 2021-02-17 | — | — | EP | claimed |
| WO-2019191229-A1 | COMPOUNDS FOR TREATING HUNTINGTON'S DISEASE | PTC THERAPEUTICS, INC. (US) | 2019-10-03 | — | — | WO | claimed |
| EP-1832624-B1 | Use of cerium dioxide for the stabilization of organic polymers against free radicals | BYK CHEMIE GMBH (DE) | 2009-05-13 | — | — | EP | claimed |
| CN-100345830-C | Condensed heteroaryl derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 2007-10-31 | — | — | CN | claimed |
| EP-1832624-A1 | Stabilization of organic polymers against free radicals | Byk-Chemie GmbH (DE) | 2007-09-12 | — | — | EP | claimed |
| US-20060073280-A1 | Method for producing uv abbsorption layers on substrates | BAUER MICHAEL | 2006-04-06 | — | — | US | claimed |
| EP-1304351-B1 | Uv stabilized, impact modified polyester/polycarbonate blends | GEN ELECTRIC (US) | 2006-01-04 | — | — | EP | claimed |
| CN-1703287-A | Method for forming UV-absorbing layer on substrate | CIBA SC HOLDING AG (CH) | 2005-11-30 | — | — | CN | claimed |
| EP-1558402-A2 | METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES | Ciba Specialty Chemicals Holding Inc. (CH) | 2005-08-03 | — | — | EP | claimed |
| CN-1629145-A | Condensed heteroaryl derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 2005-06-22 | — | — | CN | claimed |
| WO-2004035667-A2 | METHOD FOR PRODUCING UV ABSORPTION LAYERS ON SUBSTRATES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2004-04-29 | — | — | WO | claimed |
| US-6630527-B2 | Cycloaliphatic polyester resin and a linear polycarbonate resin; a rubber grafted ABS impact modifier; an additive composition, comprising a hindered amine light stabilizer | GENERAL ELECTRIC COMPANY | 2003-10-07 | — | — | US | claimed |
| CN-1426398-A | Fused heteroaryl derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 2003-06-25 | — | — | CN | claimed |
| US-20030109629-A1 | UV stabilized, impact modified polyester/polycarbonate blends, articles, and methods of manufacture thereof | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2003-06-12 | — | — | US | claimed |
| EP-1304351-A1 | Uv stabilized, impact modified polyester/polycarbonate blends | GENERAL ELECTRIC COMPANY (US) | 2003-04-23 | — | — | EP | claimed |
| JP-6009503-A | — | — | None | — | — | JP | disclosed |
| JP-9048760-A | — | — | None | — | — | JP | disclosed |
| EP-0280654-B1 | PROCESS FOR IMPROVING THE PHOTOCHEMICAL STABILITY OF DYEINGS ON FIBROUS POLYESTER MATERIALS | CIBA-GEIGY AG (CH) | 1992-05-13 | — | — | EP | disclosed |
| US-4895981-A | Using ultraviolet absorber | CIBA-GEIGY CORPORATION (US) | 1990-01-23 | — | — | US | disclosed |
| EP-0280654-A1 | Process for improving the photochemical stability of dyeings on fibrous polyester materials | CIBA-GEIGY AG (CH) | 1988-08-31 | — | — | EP | disclosed |