Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.52 |
| ▸ | STS | P08842 | 5/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795598 | 0.88 | MEN1 (0.60) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6800721 | 0.85 | MEN1 (0.63) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL27571949 | 0.84 | MEN1 (0.54) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6798512 | 0.83 | MEN1 (0.55) | CYP19A1MEN1NPC1KMT2APDK1 | |
| SCHEMBL6801408 | 0.82 | MEN1 (0.55) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6801145 | 0.80 | GAA (0.54) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6806206 | 0.80 | CYP19A1 (0.56) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6802293 | 0.80 | MEN1 (0.45) | MEN1NPC1KMT2APDK1PDK2 | |
| SCHEMBL6806386 | 0.76 | CYP19A1 (0.64) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6800139 | 0.76 | STS (0.55) | CYP19A1STSCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |