Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 12/20 | 0.52 |
| ▸ | STS | P08842 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27545499 | 0.84 | MEN1 (0.54) | MEN1KMT2ANPC1ALDH1A1NPSR1 | |
| SCHEMBL6795598 | 0.84 | MEN1 (0.60) | MEN1KMT2ACYP19A1STSCA1 | |
| SCHEMBL6800721 | 0.83 | MEN1 (0.63) | MEN1KMT2ACYP19A1STSCA1 | |
| SCHEMBL6800779 | 0.83 | MEN1 (0.55) | MEN1KMT2ACYP19A1NPC1ALDH1A1 | |
| SCHEMBL6800942 | 0.82 | CYP19A1 (0.52) | MEN1KMT2ACYP19A1STSCA1 | |
| SCHEMBL6802630 | 0.80 | MEN1 (0.55) | MEN1KMT2ANPC1ALDH1A1NPSR1 | |
| SCHEMBL6801145 | 0.78 | GAA (0.54) | MEN1KMT2ACYP19A1STSCA1 | |
| SCHEMBL6796669 | 0.78 | CYP19A1 (0.54) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6797851 | 0.75 | CYP19A1 (0.67) | CYP19A1STSCA1CA2CA9 | |
| SCHEMBL6801011 | 0.74 | CYP19A1 (0.61) | CYP19A1STSCA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |