SCHEMBL680098

SCHEMBL680098

C[Si](C)(O)CCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.54
ALDH1A1 P00352 2/20 0.45
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44
CASP1 P29466 1/20 0.44
HSD17B10 Q99714 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
TAAR1 Q96RJ0 3/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
ATM Q13315 1/20 0.43
KEAP1 Q14145 1/20 0.43
CYP2A6 P11509 1/20 0.42
HTR2A P28223 1/20 0.42
LOXL2 Q9Y4K0 1/20 0.42
KCNH2 Q12809 1/20 0.41
IDO1 P14902 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4494444 0.86 HDAC3 (0.47) TDP1SMN1; SMN2
SCHEMBL10431545 0.86 TDP1 (0.54) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL16550634 0.80 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL9622329 0.80 TDP1 (0.59) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL9622811 0.80 TDP1 (0.59) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL6420860 0.80 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL3389806 0.80 TDP1 (0.52) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL9622333 0.80 TDP1 (0.59) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL15870660 0.79 TDP1 (0.46) TDP1ALDH1A1HPGDALOX15ALOX12
SCHEMBL15125416 0.77 TDP1 (0.56) TDP1ALDH1A1HPGDALOX15ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1863875-B1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MAT INC (DE) 2009-12-09 EP claimed
US-20090068475-A1 Self-Adhesive Addition-Crosslinking Silicon Rubber Blends, A Method For The Production Thereof, Methods For Producing Composite Moulded Parts And The Use Thereof MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2009-03-12 US claimed
JP-2008537967-A 2008-10-02 JP claimed
US-7347970-B2 Biocides based on silanol terminated silanes and siloxanes UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-03-25 US claimed
EP-1863875-A1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF Momentive Performance Materials GmbH (DE) 2007-12-12 EP claimed
WO-2006100098-A1 SELF-ADHESIVE ADDITION CROSS LINKING SILICON-RUBBER BLENDS, METHOD FOR THE PRODUCTION THEREOF, METHOD FOR PRODUCING COMPOSITE MOULDED PARTS AND THE USE THEREOF MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2006-09-28 WO claimed
US-20060194764-A1 Biocides based on silanol terminated silanes and siloxanes UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2006-08-31 US claimed
WO-2006028491-A1 BIOCIDES BASED ON SILANOL TERMINATED SILANES AND SILOXANES UNIVERSITY OF FLORIDA (US) 2006-03-16 WO claimed
EP-3455282-B1 POLYSILOXANE HYDRAULIC FLUIDS COMMW SCIENT IND RES ORG (AU) 2023-11-01 EP disclosed
CN-106146851-B Photocurable composition and cured product containing same 信越化学工业株式会社 2020-10-23 CN disclosed
EP-3093303-B1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHINETSU CHEMICAL CO (JP) 2019-08-28 EP disclosed
WO-2017126562-A1 NOVEL ISOCYANIDE COMPOUND AND HYDROSILYLATION REACTION CATALYST 信越化学工業株式会社 2017-07-27 WO disclosed
US-20160333171-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-11-17 US disclosed
EP-3093303-A1 PHOTOCURABLE COMPOSITION AND CURED PRODUCT Shin-Etsu Chemical Co., Ltd. (JP) 2016-11-16 EP disclosed
EP-1136122-A1 TRANSITION METAL CATALYSTS AND PROCESSES FOR PRODUCING $g(a)-OLEFIN AND VINYL COMPOUND POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-09-26 EP disclosed
EP-1125928-A1 TRANSITION METAL COMPOUNDS, CATALYSTS FOR THE PRODUCTION OF ALPHA-OLEFINS AND PROCESS THEREFOR IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-08-22 EP disclosed
EP-1106249-A1 CATALYST FOR $g(a)-OLEFIN PRODUCTION AND PROCESS FOR PRODUCING $g(a)-OLEFIN IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-06-13 EP disclosed
EP-1026176-A1 CATALYST FOR OLEFIN POLYMER PRODUCTION, PROCESS FOR PRODUCING THE SAME, AND PROCESS FOR PRODUCING OLEFIN POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2000-08-09 EP disclosed
EP-0945471-A1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR THE PRODUCTION OF OLEFIN POLYMERS, AND PROCESSES FOR THE PRODUCTION OF STYRENE POLYMERS IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1999-09-29 EP disclosed
US-4070313-A PHENOLIC RESOLE, BLOWING AGENT, POLYSILOXANE UNION CARBIDE CORPORATION (US) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060194764-A1 Biocides based on silanol terminated silanes and siloxanes MSR1, S1PR3, TAS2R3 TDP1 3943/4885ALDH1A1 3747/4885HPGD 3059/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.