Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622333 | 0.84 | TDP1 (0.59) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL9622811 | 0.84 | TDP1 (0.59) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL10431545 | 0.80 | TDP1 (0.54) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL680098 | 0.80 | TDP1 (0.54) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL1482484 | 0.79 | TDP1 (0.59) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL5805498 | 0.78 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL28524207 | 0.78 | TDP1 (0.52) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL23532697 | 0.78 | TDP1 (0.57) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| SCHEMBL5805322 | 0.77 | TDP1 (0.50) | TDP1ALDH1A1HPGDALOX15ALOX12 | |
| Hydrogen Peroxide SCHEMBL10839871 | 0.76 | TDP1 (0.71) | TDP1ALDH1A1HPGDALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106959-A | Intermediates for ceramics, gels, films, optical fibers, polymerization catalysts and silicone curing agents | RHONE-POULENC, INC. (US) | 1992-04-21 | — | — | US | disclosed |
| US-5017694-A | With silanol-type compounds | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| US-5017695-A | With cerium ammonium nitrate and silanol-type compound | RHONE-POULENC, INC. (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0324671-A2 | Alkoxy-type derivatives of trivalent metals of group 3b, and their preparation | RHONE-POULENC CHIMIE (FR) | 1989-07-19 | — | — | EP | disclosed |
| EP-0319383-A2 | Process for the fabrication of cerium hydrocarbonsilyloxides by transetherification of cerium alkoxides | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |
| EP-0319384-A2 | Cerium hydrocarbonsilyloxydes and process for their manufacture | RHONE-POULENC CHIMIE (FR) | 1989-06-07 | — | — | EP | disclosed |