Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.78 |
| ▸ | FCER2 | P06734 | 14/20 | 0.68 |
| ▸ | MMP2 | P08253 | 4/20 | 0.67 |
| ▸ | MMP3 | P08254 | 3/20 | 0.67 |
| ▸ | MMP7 | P09237 | 3/20 | 0.67 |
| ▸ | MMP9 | P14780 | 2/20 | 0.67 |
| ▸ | MMP8 | P22894 | 2/20 | 0.67 |
| ▸ | MMP13 | P45452 | 2/20 | 0.67 |
| ▸ | MMP14 | P50281 | 2/20 | 0.67 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4421135 | 0.93 | FCER2 (0.80) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL22847464 | 0.83 | MMP1 (0.91) | MMP1FCER2MMP2MMP3MMP7 | |
| Batimastat SCHEMBL22803645 | 0.80 | MMP1 (1.00) | MMP1FCER2MMP2MMP3MMP7 | |
| Batimastat SCHEMBL20793035 | 0.80 | MMP1 (1.00) | MMP1FCER2MMP2MMP3MMP7 | |
| Batimastat SCHEMBL10052355 | 0.80 | MMP1 (1.00) | MMP1FCER2MMP2MMP3MMP7 | |
| SCHEMBL23258231 | 0.80 | MMP1 (0.86) | MMP1FCER2MMP2MMP3MMP7 | |
| Batimastat SCHEMBL4333 | 0.80 | MMP1 (1.00) | MMP1FCER2MMP2MMP3MMP7 | |
| Batimastat SCHEMBL12336015 | 0.80 | MMP1 (1.00) | MMP1FCER2MMP2MMP3MMP7 | |
| Batimastat SCHEMBL12561510 | 0.80 | MMP1 (1.00) | MMP1FCER2MMP2MMP3MMP7 | |
| Batimastat SCHEMBL17521974 | 0.80 | MMP1 (1.00) | MMP1FCER2MMP2MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6790834-B1 | Cytostatic agents | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 2004-09-14 | — | — | US | disclosed |
| US-6462023-B1 | SUCH AS 2-HYDROXY-HYDROXYCARBAMOYL-METHYL)-4-METHYL-PENTANOYLAMINE)-2-PHENYL -ETHANOIC ACID CYCLOPENTYL ESTER; INHIBITING HYPERPROLIFERATIVE TUMOURGENIC CELLS SUCH AS MELANOMA AND/OR LYMPHOMA CELLS | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 2002-10-08 | — | — | US | disclosed |
| EP-0925278-B1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARM (GB) | 2002-07-17 | — | — | EP | disclosed |
| US-6169075-B1 | ANTITUMOR AGENT INHIBITING THE PROLIFERATION OF A RANGE OF RAPIDLY DIVIDING TUMOUR CELLS LIKE MELANOMA AND/OR LYMPHOMA CELLS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-01-02 | — | — | US | disclosed |
| EP-0925278-A1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1999-06-30 | — | — | EP | disclosed |
| WO-1998011063-A1 | CYTOSTATIC HYDROXAMIC ACID DERIVATIVES | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1998-03-19 | — | — | WO | disclosed |