Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592141 | 0.79 | CYP1A2 (0.44) | MAPTTDP1GAA | |
| SCHEMBL17165345 | 0.79 | HTT (0.41) | GAA | |
| SCHEMBL20508956 | 0.77 | TDP1 (0.37) | L3MBTL1MAPTTDP1GAAPOLB | |
| SCHEMBL2060117 | 0.76 | KDM4E (0.35) | MAPT | |
| SCHEMBL9656457 | 0.75 | — | — | |
| SCHEMBL17060282 | 0.74 | PDPK1 (0.32) | — | |
| SCHEMBL9658138 | 0.73 | — | — | |
| SCHEMBL10047090 | 0.73 | L3MBTL1 (0.42) | L3MBTL1MAPTTDP1POLBNPSR1 | |
| SCHEMBL5066802 | 0.73 | ADORA1 (0.37) | MAPTGAA | |
| SCHEMBL9176115 | 0.73 | GDA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6723727-B1 | VITRONECTIN RECEPTOR ANTAGONISTS; INHIBITORS OF BONE RESORPTION; OSTEOPOROSIS | HOECHST AKTIENGESELLSCHAFT (DE) | 2004-04-20 | — | — | US | disclosed |