Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 17/20 | 0.50 |
| ▸ | ITGAV | P06756 | 17/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 8/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 4/20 | 0.50 |
| ▸ | ITGB6 | P18564 | 3/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773294 | 0.92 | ITGB3 (0.52) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6768513 | 0.85 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6773136 | 0.83 | ITGB3 (0.52) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6771727 | 0.83 | ITGB1 (0.48) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6767615 | 0.82 | ITGB3 (0.49) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6778668 | 0.82 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6772750 | 0.81 | ITGB3 (0.55) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6774218 | 0.81 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6769604 | 0.81 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGB5ITGB6 | |
| SCHEMBL6771102 | 0.79 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGB5ITGB6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720315-B2 | FOR INHIBITING BONE RESORPTION, PERIODONTAL DISEASE, OSTEOPOROSIS, HUMORAL HYPERCALCEMIA OF MALIGNANCY, PAGET'S DISEASE, TUMOR METASTASIS, SOLID TUMOR GROWTH, ANGIOGENESIS, MACULAR DEGENERATION AND DIABETIC RETINOPATHY RETINOPATHY | PHARMACIA CORPORATION | 2004-04-13 | — | — | US | disclosed |