Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.51 |
| ▸ | CTSV | O60911 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4449529 | 0.96 | CTSS (0.54) | CTSSCTSVCTSLACE2CTSK | |
| SCHEMBL5104927 | 0.95 | CTSS (0.54) | CTSSCTSVCTSLACE2CTSK | |
| SCHEMBL4449120 | 0.95 | CTSS (0.54) | CTSSCTSVCTSLACE2CTSK | |
| SCHEMBL13677233 | 0.95 | CTSS (0.54) | CTSSCTSVCTSLACE2CTSK | |
| SCHEMBL6798884 | 0.91 | CTSS (0.52) | CTSSCTSVCTSLACE2CTSK | |
| SCHEMBL7096816 | 0.90 | CTSS (0.58) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL13677254 | 0.90 | CTSS (0.58) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL4457823 | 0.90 | CTSS (0.58) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL4451252 | 0.90 | CTSS (0.58) | CTSSCTSVCTSLCTSKCCR1 | |
| SCHEMBL13677368 | 0.88 | CTSS (0.66) | CTSSCTSVCTSLACE2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138250-A1 | Inhibitors of cruzipain and other cysteine proteases | GRUNENTHAL GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138250-A1 | Inhibitors of cruzipain and other cysteine proteases | CPN1, CTRL, CPA1 | CTSS 39/4885CTSV 27/4885CTSL 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.