Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | RRM1 | P23921 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 4/20 | 0.38 |
| ▸ | FNTB | P49356 | 4/20 | 0.38 |
| ▸ | PGGT1B | P53609 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801475 | 1.00 | CNR1 (0.48) | CNR1CNR2C3AR1HDAC3HDAC4 | |
| SCHEMBL14090782 | 0.83 | C3AR1 (0.47) | CNR1CNR2C3AR1NPSR1FOLH1 | |
| SCHEMBL4565586 | 0.83 | C3AR1 (0.47) | CNR1CNR2C3AR1NPSR1FOLH1 | |
| SCHEMBL1724846 | 0.82 | FOLH1 (0.40) | C3AR1FOLH1NPY4RGNPATNPY1R | |
| SCHEMBL4552682 | 0.82 | FOLH1 (0.40) | C3AR1FOLH1NPY4RGNPATNPY1R | |
| SCHEMBL31184339 | 0.81 | FOLH1 (0.39) | C3AR1FOLH1NPY4RGNPATNPY1R | |
| SCHEMBL9661344 | 0.80 | C3AR1 (0.43) | CNR1CNR2C3AR1NPSR1FOLH1 | |
| SCHEMBL9661340 | 0.80 | C3AR1 (0.43) | CNR1CNR2C3AR1NPSR1FOLH1 | |
| Hydrochloric Acid SCHEMBL9659549 | 0.79 | C3AR1 (0.42) | CNR1CNR2C3AR1NPSR1FOLH1 | |
| Hydrochloric Acid SCHEMBL9659539 | 0.79 | C3AR1 (0.42) | CNR1CNR2C3AR1NPSR1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040053864-A1 | Methods and compositions for control of bone formation via modulation of neuropeptide y activity | BAYLOR COLLEGE OF MEDICINE | 2004-03-18 | — | — | US | disclosed |
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001053477-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF BONE FORMATION VIA MODULATION OF NEUROPEPTIDE Y ACTIVITY | BAYLOR COLLEGE OF MEDICINE (US) | 2001-07-26 | — | — | WO | disclosed |
| US-6127414-A | NPY antagonists | ASTRA AKTIEBOLAG (SE) | 2000-10-03 | — | — | US | disclosed |
| EP-1017672-A1 | NEW NPY ANTAGONISTS | AstraZeneca AB (SE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999063990-A1 | NEW USE | ASTRAZENECA AB (SE) | 1999-12-16 | — | — | WO | disclosed |
| WO-1999018948-A1 | NEW USE OF NPY ANTAGONISTS | ASTRA AKTIEBOLAG (SE) | 1999-04-22 | — | — | WO | disclosed |
| WO-1999015498-A1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 1999-04-01 | — | — | WO | disclosed |