SCHEMBL4552682

SCHEMBL4552682

CC(C)(C)C(=O)NC(CCCNC(=N)N)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 5/20 0.40
▸ C3AR1 Q16581 1/20 0.38
▸ MEN1 O00255 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ NOD1 Q9Y239 2/20 0.37
▸ GRIA1 P42261 1/20 0.36
▸ NPY4R P50391 5/20 0.35
▸ NPY1R P25929 3/20 0.35
▸ NPY2R P49146 3/20 0.35
▸ NPY5R Q15761 3/20 0.35
▸ ITGB3 P05106 1/20 0.34
▸ ITGA2B P08514 1/20 0.34
▸ POLB P06746 1/20 0.34
▸ GNPAT O15228 1/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1724846 1.00 FOLH1 (0.40) FOLH1C3AR1MEN1GAAKMT2A
SCHEMBL31184339 0.90 FOLH1 (0.39) FOLH1C3AR1MEN1GAAKMT2A
SCHEMBL24805405 0.88 C3AR1 (0.48) FOLH1C3AR1MEN1GAAKMT2A
SCHEMBL20275937 0.87 NOD1 (0.38) FOLH1C3AR1MEN1GAAKMT2A
SCHEMBL18464241 0.86 NPY4R (0.42) FOLH1MEN1GAAKMT2AGRIA1
SCHEMBL1070697 0.85 ALDH1A1 (0.41) FOLH1C3AR1MEN1KMT2ANOD1
SCHEMBL1070699 0.85 ALDH1A1 (0.41) FOLH1C3AR1MEN1KMT2ANOD1
SCHEMBL29005731 0.84 C3AR1 (0.43) FOLH1C3AR1MEN1KMT2ANOD1
SCHEMBL12971304 0.84 C3AR1 (0.43) FOLH1C3AR1MEN1KMT2ANOD1
SCHEMBL16589746 0.83 GRIA1 (0.45) GRIA1NPY4RNPY1RNPY2RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3272764-B1 METHOD FOR AFFINITY CHROMATOGRAPHY NOVARTIS AG (CH) 2024-02-07 — — EP claimed
EP-2059258-B1 ARGININE WASH IN PROTEIN PURIFICATION USING AFFINITY CHROMATOGRAPHY WYETH LLC (US) 2019-11-13 — — EP claimed
EP-2714714-B1 WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY NOVARTIS AG (CH) 2018-06-20 — — EP claimed
EP-2513134-B1 WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY NOVARTIS AG (CH) 2017-09-06 — — EP claimed
EP-1568710-A2 Antibody purification method Ajinomoto Co., Inc. (JP) 2005-08-31 — — EP claimed
EP-3272764-B1 METHOD FOR AFFINITY CHROMATOGRAPHY NOVARTIS AG (CH) 2024-02-07 — — EP disclosed
WO-2022266753-A1 BIVALENT COMPOUNDS, CONJUGATES AND USES THEREOF Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2022-12-29 — — WO disclosed
US-10913972-B2 5,5-disubstituted luciferins and their use in luciferase-based assays PROMEGA CORPORATION (US) 2021-02-09 — — US disclosed
US-10400264-B2 5,5-disubstituted luciferins and their use in luciferase-based assays PROMEGA CORPORATION (US) 2019-09-03 — — US disclosed
US-20180155762-A1 5,5-DISUBSTITUTED LUCIFERINS AND THEIR USE IN LUCIFERASE-BASED ASSAYS JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-06-07 — — US disclosed
US-20180155762-A1 5,5-DISUBSTITUTED LUCIFERINS AND THEIR USE IN LUCIFERASE-BASED ASSAYS JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2018-06-07 — — US disclosed
EP-2513134-B1 WASH SOLUTION AND METHOD FOR AFFINITY CHROMATOGRAPHY NOVARTIS AG (CH) 2017-09-06 — — EP disclosed
US-20100304273-A1 PROTON CONDUCTING MEMBRANES FOR FUEL CELLS HAVING A PROTON GRADIENT AND METHODS FOR PREPARING SAID MEMBRANES COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2010-12-02 — — US disclosed
EP-1568710-B1 Antibody purification method AJINOMOTO KK (JP) 2009-12-23 — — EP disclosed
EP-1568710-A2 Antibody purification method Ajinomoto Co., Inc. (JP) 2005-08-31 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180155762-A1 5,5-DISUBSTITUTED LUCIFERINS AND THEIR USE IN LUCIFERASE-BASED ASSAYS GLB1, LUC7L2, GUSB FOLH1 449/4885C3AR1 4674/4885MEN1 2121/4885
US-10400264-B2 5,5-disubstituted luciferins and their use in luciferase-based assays GLB1, GUSB, LUC7L2 FOLH1 500/4885C3AR1 4698/4885MEN1 2128/4885
US-10913972-B2 5,5-disubstituted luciferins and their use in luciferase-based assays GLB1, LUC7L2, GUSB FOLH1 449/4885C3AR1 4674/4885MEN1 2121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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