⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2240670 | 1.00 | — | — | |
| SCHEMBL2649338 | 0.97 | ADH1B (0.34) | — | |
| SCHEMBL441910 | 0.97 | ADH1B (0.34) | — | |
| SCHEMBL8941237 | 0.94 | — | — | |
| SCHEMBL962973 | 0.94 | — | — | |
| SCHEMBL1482074 | 0.88 | — | — | |
| SCHEMBL1482073 | 0.88 | — | — | |
| SCHEMBL29860701 | 0.82 | ADH1B (0.36) | — | |
| SCHEMBL9112176 | 0.75 | HRH3 (0.37) | — | |
| SCHEMBL11144495 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040023882-A1 | PTH derivatives resistant to skin proteases | THERATECHNOLOGIES INC. (CA) | 2004-02-05 | — | — | US | disclosed |
| WO-2003097690-A2 | PTH DERIVATIVES RESISTANT TO SKIN PROTEASES | THERATECHNOLOGIES INC. (CA) | 2003-11-27 | — | — | WO | disclosed |
| US-6323235-B1 | CARDIOVASCULAR DISORDERS, ANTIISCHEMIC AGENTS AND ENZYME INHIBITORS | OHTAKE ATSUSHI (JP) | 2001-11-27 | — | — | US | disclosed |
| US-6043264-A | A THROMBOXANE A2 RECEPTOR ANTAGONIST FOR TREATING HYPERTENSION, THROMBOSIS, ISCHEMIC HEART DISEASES, CIRCULATORY DISEASES, ARTERIOSCLEROSIS, PLATELET FUNCTION DISORDER, HYPERLIPIDEMIA, NEPHRITIS OR ASTHMA | TORAY INDUSTRIES, INC. (JP) | 2000-03-28 | — | — | US | disclosed |
| EP-0751126-A1 | BENZENE-FUSED HETEROCYCLIC DERIVATIVE AND USE OF THE SAME | TORAY INDUSTRIES, INC. (JP) | 1997-01-02 | — | — | EP | disclosed |