Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 15/20 | 0.64 |
| ▸ | APOB | P04114 | 11/20 | 0.64 |
| ▸ | SMO | Q99835 | 10/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803761 | 0.93 | MTTP (0.55) | MTTPAPOBSMO | |
| SCHEMBL6799789 | 0.92 | SMO (0.54) | MTTPAPOBSMO | |
| SCHEMBL6804425 | 0.92 | MTTP (0.52) | MTTPAPOBSMO | |
| SCHEMBL6809846 | 0.91 | MTTP (0.52) | MTTPAPOBSMO | |
| SCHEMBL6801440 | 0.91 | MTTP (0.52) | MTTPAPOBSMO | |
| SCHEMBL6668494 | 0.90 | MTTP (0.51) | MTTPAPOBSMO | |
| SCHEMBL6667820 | 0.89 | SMO (0.50) | MTTPAPOBSMO | |
| SCHEMBL6808797 | 0.89 | MTTP (0.49) | MTTPAPOBSMO | |
| SCHEMBL6804573 | 0.89 | SMO (0.51) | MTTPAPOBSMO | |
| SCHEMBL6801403 | 0.88 | SMO (0.50) | MTTPAPOBSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | MTTP 108/4885APOB 1/4885SMO 4390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.