SCHEMBL680185

SCHEMBL680185

Cc1ccc2c3ccccc3n(-c3ccc(C)s3)c2c1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.38
LMNA P02545 3/20 0.38
HTT P42858 2/20 0.38
KDM4E B2RXH2 2/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
RORC P51449 2/20 0.35
KIF11 P52732 2/20 0.35
GPR3 P46089 1/20 0.34
POLB P06746 1/20 0.33
BCHE P06276 1/20 0.32
ACHE P22303 1/20 0.32
TP53 P04637 1/20 0.32
NTRK1 P04629 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31
ALKBH5 Q6P6C2 1/20 0.31
FTO Q9C0B1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680511 0.92 BCHE (0.38) MAPTLMNAHTTKDM4EATM
SCHEMBL8932231 0.90 KDM4E (0.43) MAPTLMNAHTTKDM4EATM
SCHEMBL13957096 0.83 MAPT (0.40) MAPTLMNAHTTKDM4EATM
SCHEMBL17051400 0.83 MAPT (0.35) MAPTLMNAHTTKDM4ERORC
SCHEMBL13957098 0.78 KDM4E (0.57) MAPTLMNAHTTKDM4EATM
SCHEMBL4401736 0.78 KDM4E (0.57) MAPTLMNAHTTKDM4EATM
SCHEMBL13912325 0.76 KDM4E (0.52) MAPTLMNAHTTKDM4EATM
SCHEMBL883474 0.76 KDM4E (0.67) MAPTLMNAHTTKDM4EATM
SCHEMBL680760 0.76 KDM4E (0.55) MAPTLMNAHTTKDM4EATM
SCHEMBL22926684 0.75 LMNA (0.41) MAPTLMNAHTTKDM4EATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed