SCHEMBL680186

SCHEMBL680186

CCC(C)COc1ccc(C2(c3cc(C)ccc3C)c3cc(B4OC(C)(C)C(C)(C)O4)ccc3-c3ccc(B4OC(C)(C)C(C)(C)O4)cc32)cc1OCC(C)CC

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL680800 0.82 AAK1 (0.31) AAK1
SCHEMBL14156866 0.82
SCHEMBL11956148 0.79 LPL (0.37) HIF1A
SCHEMBL18561059 0.78
SCHEMBL13326297 0.76 TLR8 (0.34)
SCHEMBL12337056 0.74 POLB (0.31)
SCHEMBL13326300 0.73 TLR8 (0.32)
SCHEMBL12681702 0.72 LPL (0.41) HIF1A
SCHEMBL13217928 0.72 AAK1 (0.31) AAK1HIF1A
SCHEMBL12595641 0.71 TLR8 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8053547-B2 Conjugated polymers and blends containing carbazole, representation and use thereof MERCK PATENT GMBH (DE) 2011-11-08 US disclosed
EP-1932866-B1 Blends comprising conjugated carbazole polymers, synthesis and usage thereof MERCK PATENT GMBH (DE) 2011-07-13 EP disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-20110068304-A1 Conjugated Polymers and Blends Containing Carbazole, Representation and Use Thereof MERCK PATENT GMBH (DE) 2011-03-24 US disclosed
US-7910687-B2 Conjugated polymers containing arylamine units, the representation thereof and the use of the same MERCK PATENT GMBH (DE) 2011-03-22 US disclosed
US-7910687-B2 Conjugated polymers containing arylamine units, the representation thereof and the use of the same MERCK PATENT GMBH (DE) 2011-03-22 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
US-7834136-B2 Conjugated polymers and blends containing carbazole, representation and use thereof COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2010-11-16 US disclosed
US-7772323-B2 Conjugated copolymers, representation and use thereof MERCK PATENT GMBH (DE) 2010-08-10 US disclosed
EP-1641894-B1 NOVEL MATERIALS FOR ELECTROLUMINESCENCE MERCK PATENT GMBH (DE) 2009-01-21 EP disclosed
EP-1932866-A1 Blends comprising conjugated carbazole polymers, synthesis and usage thereof MERCK PATENT GmbH (DE) 2008-06-18 EP disclosed
EP-1592729-B1 CONJUGATED POLYMERS AND BLENDS CONTAINING CARBAZOLE, REPRESENTATION AND USE THEREOF MERCK PATENT GMBH (DE) 2008-04-23 EP disclosed
US-7288617-B2 Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof MERCK PATENT GMBH (DE) 2007-10-30 US disclosed
US-7288617-B2 Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof MERCK PATENT GMBH (DE) 2007-10-30 US disclosed