Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1678458 | 0.89 | — | — | |
| SCHEMBL16430876 | 0.88 | TLR2 (0.40) | TLR2KMT2ASMN1; SMN2HSD17B10GNAI3 | |
| Hydrochloric Acid SCHEMBL28988641 | 0.87 | — | — | |
| SCHEMBL2226371 | 0.84 | NAAA (0.50) | TLR2KMT2ASMN1; SMN2HSD17B10GNAI3 | |
| SCHEMBL23890497 | 0.81 | KMT2A (0.45) | KMT2ASMN1; SMN2HSD17B10GNAI3GNAO1 | |
| SCHEMBL15199084 | 0.81 | KMT2A (0.45) | KMT2ASMN1; SMN2HSD17B10GNAI3GNAO1 | |
| SCHEMBL13753926 | 0.81 | KMT2A (0.45) | KMT2ASMN1; SMN2HSD17B10GNAI3GNAO1 | |
| SCHEMBL15199085 | 0.81 | KMT2A (0.45) | KMT2ASMN1; SMN2HSD17B10GNAI3GNAO1 | |
| SCHEMBL13255685 | 0.81 | KMT2A (0.45) | KMT2ASMN1; SMN2HSD17B10GNAI3GNAO1 | |
| SCHEMBL13321817 | 0.81 | KMT2A (0.45) | KMT2ASMN1; SMN2HSD17B10GNAI3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040063701-A1 | Piperidine derivatives and anti-platelet agents containing the same | AJINOMOTO CO., INC (JP) | 2004-04-01 | — | — | US | claimed |
| US-20020147195-A1 | Piperidine derivatives and anti-platelet agents containing the same | AJINOMOTO CO., INC. (JP) | 2002-10-10 | — | — | US | claimed |
| US-20020019533-A1 | PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME | MAKINO SHINGO (JP) | 2002-02-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019533-A1 | PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME | HTR2A, PDGFRA, PDGFRB | TLR2 657/4885KMT2A 1761/4885SMN1; SMN2 2817/4885 |
| US-20020147195-A1 | Piperidine derivatives and anti-platelet agents containing the same | HTR2A, PDGFRA, PDGFRB | TLR2 657/4885KMT2A 1761/4885SMN1; SMN2 2817/4885 |
| US-20040063701-A1 | Piperidine derivatives and anti-platelet agents containing the same | HTR2A, PDGFRA, PDGFRB | TLR2 657/4885KMT2A 1761/4885SMN1; SMN2 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.