Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13198868 | 1.00 | TLR8 (0.36) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL11957248 | 0.94 | TLR8 (0.33) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL13376510 | 0.93 | TLR8 (0.32) | TLR8MCHR1 | |
| SCHEMBL14441622 | 0.93 | TLR8 (0.32) | TLR8MCHR1 | |
| SCHEMBL13595440 | 0.88 | BACE1 (0.33) | GAA | |
| SCHEMBL13326313 | 0.87 | TLR8 (0.33) | TLR8MCHR1PDE4APDE4BPDE4C | |
| SCHEMBL13595416 | 0.87 | TLR8 (0.31) | TLR8MCHR1AAK1 | |
| SCHEMBL20198338 | 0.87 | TLR8 (0.31) | TLR8MCHR1 | |
| SCHEMBL679086 | 0.87 | TUBB4A (0.34) | TLR8IGF1R | |
| SCHEMBL13816600 | 0.86 | TLR8 (0.34) | TLR8MCHR1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264720-A1 | METHOD FOR THE PRODUCTION OF POLYMERS | MERCK PATENT GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| US-20160264720-A1 | METHOD FOR THE PRODUCTION OF POLYMERS | MERCK PATENT GMBH (DE) | 2016-09-15 | — | — | US | disclosed |
| US-9415370-B2 | Method for the production of polymers | MERCK PATENT GMBH (DE) | 2016-08-16 | — | — | US | disclosed |
| US-9415370-B2 | Method for the production of polymers | MERCK PATENT GMBH (DE) | 2016-08-16 | — | — | US | disclosed |
| EP-2273512-B1 | Conjugated polymers comprising triarylamine-arylenevinylene units, synthesis and use of the same | MERCK PATENT GMBH (DE) | 2016-07-20 | — | — | EP | disclosed |
| US-8679644-B2 | Electroluminescent polymers containing planar arylamine units, the preparation and use thereof | MERCK PATENT GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-8679644-B2 | Electroluminescent polymers containing planar arylamine units, the preparation and use thereof | MERCK PATENT GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-8173276-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173276-B2 | Materials for electroluminescence and the utilization thereof | MERCK PATENT GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8053547-B2 | Conjugated polymers and blends containing carbazole, representation and use thereof | MERCK PATENT GMBH (DE) | 2011-11-08 | — | — | US | disclosed |
| US-20060058524-A1 | Method for the production of aryl-aryl coupled compounds | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2006-03-16 | — | — | US | disclosed |
| EP-1537161-A1 | METHOD FOR THE PRODUCTION OF ARYL-ARYL COUPLED COMPOUNDS | Covion Organic Semiconductors GmbH (DE) | 2005-06-08 | — | — | EP | disclosed |
| US-20050038223-A1 | Conjugated polymers containing spirobifluorene units and the use thereof | MERCK PATENT GMBH (DE) | 2005-02-17 | — | — | US | disclosed |
| EP-1381639-B1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS (DE) | 2004-09-08 | — | — | EP | disclosed |
| US-20040135131-A1 | Conjugated polymers containing spirobifluorene units and fluorene units, and the use thereof | MERCK PATENT GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
| EP-1427768-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2004022626-A1 | METHOD FOR THE PRODUCTION OF ARYL-ARYL COUPLED COMPOUNDS | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2004-03-18 | — | — | WO | disclosed |
| EP-1381639-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | Covion Organic Semiconductors GmbH (DE) | 2004-01-21 | — | — | EP | disclosed |
| WO-2003020790-A2 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2003-03-13 | — | — | WO | disclosed |
| WO-2002077060-A1 | CONJUGATED POLYMERS CONTAINING SPIROBIFLUORENE UNITS AND FLUORENE UNITS, AND THE USE THEREOF | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-10-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058524-A1 | Method for the production of aryl-aryl coupled compounds | TYR, AHR, ARSA | TLR8 4182/4885MCHR1 2422/4885PDE4A 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.