Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 3/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | NAT1 | P18440 | 1/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802016 | 0.83 | MAOB (0.48) | MIFMAOBMAOAESR1ESR2 | |
| SCHEMBL6800031 | 0.83 | MAOB (0.48) | MIFMAOBMAOAESR1ESR2 | |
| SCHEMBL6796287 | 0.80 | MAOB (0.46) | MIFMAOBMAOACYP26A1 | |
| SCHEMBL6797976 | 0.80 | MAOB (0.46) | MIFMAOBMAOACYP26A1 | |
| SCHEMBL6940051 | 0.73 | MIF (0.51) | MIF | |
| SCHEMBL6800928 | 0.73 | CES2 (0.53) | MIFMAOBMAOACYP26A1 | |
| SCHEMBL6802315 | 0.73 | CES2 (0.53) | MIFMAOBMAOACYP26A1 | |
| SCHEMBL6806457 | 0.73 | MAOB (0.47) | MAOBMAOA | |
| SCHEMBL6799865 | 0.73 | MAOB (0.47) | MAOBMAOA | |
| SCHEMBL6794708 | 0.68 | PBRM1 (0.46) | MAOBMAOAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | MERCK & CO., INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082642-A1 | Novel estrogen receptor ligands and method III | ESRRA, ESRRB, FSHR | MIF 881/4885MAOB 1020/4885MAOA 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.