Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6802526 | 0.75 | KDM4E (0.40) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL9545547 | 0.74 | POLB (0.36) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL6801617 | 0.72 | KDM4E (0.38) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL6803468 | 0.72 | KDM4E (0.40) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL6800505 | 0.71 | POLB (0.38) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL6807527 | 0.71 | KDM4E (0.39) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL6807254 | 0.70 | POLB (0.39) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL9393411 | 0.68 | POLB (0.34) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL6798605 | 0.67 | KDM4E (0.35) | POLBALDH1A1LMNAKDM4E | |
| SCHEMBL28919421 | 0.63 | GRM5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743814-B2 | REACTING 4-BROMO-1,1,2-TRIFLUORO-1-BUTENE WITH 2-MERCAPTO-OXAZOLE | NIHON BAYER AGROCHEM K.K. (JP) | 2004-06-01 | — | — | US | disclosed |
| US-20030109563-A1 | Combating nematodes characterized in that trifluorobutenes of the formula (I) are allowed to act on nematodes and/or their habitat. | NIHON BAYER AGROCHIM K.K. (JP) | 2003-06-12 | — | — | US | disclosed |
| EP-1263744-A1 | NEMATICIDAL TRIFLUOROBUTENES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001066529-A1 | NEMATICIDAL TRIFLUOROBUTENES | NIHON BAYER AGROCHEM K.K. (DE) | 2001-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109563-A1 | Combating nematodes characterized in that trifluorobutenes of the formula (I) are allowed to act on nematodes and/or their habitat. | NAT1, CNR1, CTRL | POLB 2395/4885ALDH1A1 676/4885LMNA 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.