Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.32 |
| ▸ | PRNP | P04156 | 3/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10745161 | 0.81 | DRD2 (0.35) | ALDH1A1NPSR1HTR1ADRD2HTR2A | |
| SCHEMBL9545545 | 0.80 | POLB (0.38) | POLBLMNAALDH1A1KDM4ENPSR1 | |
| SCHEMBL9545376 | 0.75 | MAPT (0.30) | LMNAMAPT | |
| SCHEMBL6802436 | 0.74 | POLB (0.36) | POLBLMNAALDH1A1KDM4E | |
| SCHEMBL9545437 | 0.74 | NPC1 (0.34) | ALDH1A1KDM4ENPSR1HTR1ADRD2 | |
| SCHEMBL9868149 | 0.73 | PTGS2 (0.42) | POLBLMNANPSR1HPGDMAPT | |
| SCHEMBL9545447 | 0.72 | — | — | |
| SCHEMBL9865854 | 0.70 | HCAR1 (0.39) | LMNA | |
| SCHEMBL9867638 | 0.69 | FFAR4 (0.34) | — | |
| SCHEMBL9393411 | 0.68 | POLB (0.34) | POLBLMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993021150-A2 | ARTHROPODICIDAL ARYL SULFONATES | DUNLENA PTY. LTD. (AU) | 1993-10-28 | — | — | WO | disclosed |