Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6805378 | 0.96 | TP53 (0.42) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6540854 | 0.95 | TP53 (0.45) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6540859 | 0.95 | TP53 (0.45) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6806596 | 0.93 | TP53 (0.41) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6540404 | 0.93 | TP53 (0.41) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6677034 | 0.93 | ADRB3 (0.44) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6677084 | 0.92 | TP53 (0.45) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6804359 | 0.92 | TP53 (0.45) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6540284 | 0.92 | TP53 (0.52) | TP53MAPTMAPK1SMN1; SMN2ADRB3 | |
| SCHEMBL6540279 | 0.92 | TP53 (0.52) | TP53MAPTMAPK1SMN1; SMN2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | TP53 3318/4885MAPT 4534/4885MAPK1 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.