Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6540404 | 0.94 | TP53 (0.41) | TP53ADRB3ADRB1POLBALDH1A1 | |
| SCHEMBL6802965 | 0.93 | TP53 (0.43) | TP53ADRB3ADRB1POLBALDH1A1 | |
| SCHEMBL6540859 | 0.91 | TP53 (0.45) | TP53ADRB3ADRB1POLBALDH1A1 | |
| SCHEMBL6540854 | 0.91 | TP53 (0.45) | TP53ADRB3ADRB1POLBALDH1A1 | |
| SCHEMBL6805378 | 0.89 | TP53 (0.42) | TP53ADRB3ADRB1POLBALDH1A1 | |
| SCHEMBL6540284 | 0.89 | TP53 (0.52) | TP53ADRB3ADRB1POLBALDH1A1 | |
| SCHEMBL6540279 | 0.89 | TP53 (0.52) | TP53ADRB3ADRB1POLBALDH1A1 | |
| SCHEMBL6540385 | 0.89 | ADRB1 (0.46) | TP53ADRB3ADRB1POLBMAPT | |
| SCHEMBL6677034 | 0.88 | ADRB3 (0.44) | TP53ADRB3ADRB1POLBALDH1A1 | |
| SCHEMBL6803249 | 0.88 | TP53 (0.40) | TP53ADRB3ADRB1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | TP53 3318/4885ADRB3 150/4885ADRB1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.