Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6797228 | 0.91 | ESR1 (0.61) | CYP19A1ESR1ESR2CA12CA2 | |
| SCHEMBL27565504 | 0.85 | POLB (0.49) | CYP19A1POLBCRHBPCRHR2MAPKAPK2 | |
| SCHEMBL6799976 | 0.85 | CYP19A1 (0.50) | CYP19A1ESR1ESR2POLBCA12 | |
| SCHEMBL6801305 | 0.85 | CYP19A1 (0.55) | CYP19A1ESR1ESR2POLBCA12 | |
| SCHEMBL6800386 | 0.84 | CYP19A1 (0.54) | CYP19A1ESR1ESR2POLBCA12 | |
| SCHEMBL6799206 | 0.81 | CYP19A1 (0.49) | CYP19A1ESR1ESR2POLBCA12 | |
| SCHEMBL6799479 | 0.80 | CYP19A1 (0.50) | CYP19A1ESR1ESR2POLBCA12 | |
| SCHEMBL8328066 | 0.77 | CYP19A1 (0.44) | CYP19A1ESR1ESR2POLBCRHBP | |
| SCHEMBL6801380 | 0.77 | CYP19A1 (0.62) | CYP19A1POLBCA12CA2CA9 | |
| SCHEMBL6800189 | 0.77 | POLB (0.42) | CYP19A1POLBCRHBPCRHR2MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1308297-C | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2007-04-04 | — | — | CN | disclosed |
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| CN-1360570-A | Phenyl sulfamate derivs. | TEIKOKU HORMONE MFG CO LTD (JP) | 2002-07-24 | — | — | CN | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |