Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | HTT | P42858 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.52 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20566310 | 0.84 | SMN1; SMN2 (0.57) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL13164434 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL10807598 | 0.80 | ALDH1A1 (0.59) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL1505008 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL9393802 | 0.78 | PSMB8 (0.65) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL7905772 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL7039613 | 0.76 | ALDH1A1 (0.57) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL6814325 | 0.75 | HDAC6 (0.40) | ALDH1A1MAPTLMNAKMT2AMEN1 | |
| SCHEMBL5849619 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HTTSMN1; SMN2MAPTLMNA | |
| SCHEMBL30732411 | 0.74 | PSMB8 (0.69) | ALDH1A1HTTSMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710045-B2 | FOR CONTROLLING ANIMAL PESTS, IN PARTICULAR INSECTS, ARACHNIDS AND NEMATODES | BAYER CROPSCIENCE AG (DE) | 2004-03-23 | — | — | US | disclosed |
| US-20030187259-A1 | Heterocylic fluoroalkenyl thioethers and the use thereof as pesticides (IV) | BAYER CROPSCIENCE AG (DE) | 2003-10-02 | — | — | US | disclosed |
| EP-1311497-A1 | HETEROCYCLIC FLUOROALKENYL THIOETHERS AND THE USE THEREOF AS PESTICIDES (IV) | Bayer CropScience AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002006259-A1 | HETEROCYCLIC FLUOROALKENYL THIOETHERS AND THE USE THEREOF AS PESTICIDES (IV) | BAYER CROPSCIENCE AG (DE) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187259-A1 | Heterocylic fluoroalkenyl thioethers and the use thereof as pesticides (IV) | DDT, CYP4F2, CYP4F3 | ALDH1A1 351/4885HTT 104/4885SMN1; SMN2 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.