⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11480479 | 1.00 | — | — | |
| SCHEMBL18476761 | 1.00 | — | — | |
| SCHEMBL25284649 | 0.93 | ALOX5 (0.31) | — | |
| SCHEMBL20991379 | 0.82 | ALOX5 (0.42) | — | |
| SCHEMBL14791228 | 0.81 | BRD4 (0.33) | — | |
| SCHEMBL18665216 | 0.79 | ALOX5 (0.48) | — | |
| SCHEMBL16207203 | 0.79 | ALOX5 (0.36) | — | |
| SCHEMBL16207207 | 0.79 | ALOX5 (0.36) | — | |
| SCHEMBL910824 | 0.78 | — | — | |
| SCHEMBL12657173 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3331843-B1 | CYCLOPROPANATION OF SUBSTITUTED ALKENES | INT FLAVORS & FRAGRANCES INC (US) | 2021-03-10 | — | — | EP | disclosed |
| US-10584080-B2 | Cyclopropanation of substituted alkenes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2020-03-10 | — | — | US | disclosed |
| US-20190177247-A1 | CYCLOPROPANATION OF SUBSTITUTED ALKENES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 2019-06-13 | — | — | US | disclosed |
| US-10227269-B2 | Cyclopropanation of substituted alkenes | INTERNATIONAL FLAVORS & FRAGANCES INC. (US) | 2019-03-12 | — | — | US | disclosed |
| US-20180170830-A1 | CYCLOPROPANATION OF SUBSTITUTED ALKENES | INT FLAVORS & FRAGRANCES INC (US) | 2018-06-21 | — | — | US | disclosed |
| CN-101503345-B | 2-(2-ethyl-cyclopropyl) acetaldehyde compound and preparation thereof | SHANGHAI INST TECHNOLOGY | 2012-07-04 | — | — | CN | disclosed |
| CN-101503345-A | 2-(2-ethyl-cyclopropyl) acetaldehyde compound and preparation thereof | SHANGHAI INST TECHNOLOGY (CN) | 2009-08-12 | — | — | CN | disclosed |
| US-20040171534-A1 | GRF analogs with increased biological potency | THERATECHNOLOGIES, INC. (CA) | 2004-09-02 | — | — | US | disclosed |
| US-6458764-B1 | CHIMERIC FATTY BODY-GRF ANALOGS WITH INCREASED BIOLOGICAL POTENCY, THEIR APPLICATION AS ANABOLIC AGENTS AND IN THE DIAGNOSIS AND TREATMENT OF GROWTH HORMONE DEFICIENCIES. THE CHIMERIC FATTY BODY-GRF ANALOGS INCLUDE AN HYDROPHOBIC MOIETY | THERATECHNOLOGIES INC. (CA) | 2002-10-01 | — | — | US | disclosed |
| US-4236027-A | Novel 11-alkoxy-9-keto (or hydroxy)-prostenoic acid derivatives and method for preparing same | AMERICAN CYANAMID COMPANY (US) | 1980-11-25 | — | — | US | disclosed |
| US-4180677-A | Novel prostaglandins | AMERICAN CYANAMID COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4152524-A | BRONCHODILATORS, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1979-05-01 | — | — | US | disclosed |
| US-4076947-A | BRONCHODILATORS, HYPOTENSIVE AGENTS, ANTIULCER AGENTS | AMERICAN CYANAMID COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-3993674-A | ANTIULCER, BRONCHODILATOR, HYPOTENSIVE | AMERICAN CYANAMID COMPANY (US) | 1976-11-23 | — | — | US | disclosed |