Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.56 |
| ▸ | CTSV | O60911 | 6/20 | 0.56 |
| ▸ | CTSL | P07711 | 5/20 | 0.56 |
| ▸ | CTSK | P43235 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PER2 | O15055 | 1/20 | 0.31 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.31 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4452935 | 0.95 | CTSS (0.51) | CTSSCTSVCTSLCTSKTDP1 | |
| SCHEMBL13677357 | 0.95 | CTSS (0.51) | CTSSCTSVCTSLCTSKTDP1 | |
| SCHEMBL13677390 | 0.95 | CTSS (0.51) | CTSSCTSVCTSLCTSKTDP1 | |
| SCHEMBL6803771 | 0.83 | CTSS (0.54) | CTSSCTSVCTSLCTSK | |
| SCHEMBL4449426 | 0.82 | CTSS (0.54) | CTSSCTSVCTSLCTSKTDP1 | |
| SCHEMBL13677286 | 0.82 | CTSS (0.54) | CTSSCTSVCTSLCTSKTDP1 | |
| SCHEMBL4452957 | 0.82 | CTSS (0.54) | CTSSCTSVCTSLCTSKTDP1 | |
| SCHEMBL4450179 | 0.79 | CTSS (0.49) | CTSSCTSVCTSLCTSK | |
| SCHEMBL13677386 | 0.78 | CTSS (0.49) | CTSSCTSVCTSLCTSKTDP1 | |
| SCHEMBL13677361 | 0.78 | CTSS (0.49) | CTSSCTSVCTSLCTSKTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040138250-A1 | Inhibitors of cruzipain and other cysteine proteases | GRUNENTHAL GMBH (DE) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138250-A1 | Inhibitors of cruzipain and other cysteine proteases | CPN1, CTRL, CPA1 | CTSS 39/4885CTSV 27/4885CTSL 23/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.