SCHEMBL680389

SCHEMBL680389

CC(C)NC(=O)C=CC=Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 5/20 0.67
HDAC4 P56524 5/20 0.67
HDAC1 Q13547 5/20 0.67
HDAC2 Q92769 5/20 0.67
HDAC8 Q9BY41 5/20 0.67
HDAC6 Q9UBN7 5/20 0.67
HDAC7 Q8WUI4 4/20 0.67
HDAC10 Q969S8 4/20 0.67
HDAC11 Q96DB2 4/20 0.67
HDAC9 Q9UKV0 4/20 0.67
HDAC5 Q9UQL6 4/20 0.67
MAOB P27338 6/20 0.61
TDP1 Q9NUW8 2/20 0.58
ALDH1A1 P00352 2/20 0.51
CYP1A2 P05177 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
MAPK1 P28482 1/20 0.51
CYP2C19 P33261 1/20 0.51
MAOA P21397 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
N-Isopropylcinnamamide SCHEMBL6751570 0.88 TDP1 (0.73) HDAC3HDAC4HDAC1HDAC2HDAC8
N-Isopropylcinnamamide SCHEMBL6751573 0.88 TDP1 (0.73) HDAC3HDAC4HDAC1HDAC2HDAC8
Juarezic Acid SCHEMBL28970789 0.85 HDAC3 (0.53) HDAC3HDAC4HDAC1HDAC2HDAC8
N-Isopropylcinnamamide SCHEMBL3963268 0.85 TDP1 (0.69) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL402596 0.81 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL402595 0.81 HDAC3 (0.59) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL23077927 0.79 HDAC2 (0.96) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL10323570 0.79 HDAC2 (0.96) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL13689262 0.77 HDAC3 (0.58) HDAC3HDAC4HDAC1HDAC2HDAC8
SCHEMBL14080852 0.77 HDAC3 (0.67) HDAC3HDAC4HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8163816-B2 Production process of liquid composition, image forming process and image forming apparatus CANON KABUSHIKI KAISHA (JP) 2012-04-24 US disclosed
US-20110275774-A1 ORGANOANTIMONY COMPOUND, PROCESS FOR PREPARING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER WITH USE OF SAME, AND THE POLYMER YAMAGO SHIGERU 2011-11-10 US disclosed
US-8008414-B2 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2011-08-30 US disclosed
EP-1767539-B1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL CO LTD (JP) 2011-07-27 EP disclosed
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer OTSUKA CHEMICAL CO., LTD. (JP) 2009-12-03 US disclosed
US-20070283847-A1 PRODUCTION PROCESS OF LIQUID COMPOSITION, IMAGE FORMING PROCESS AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 2007-12-13 US disclosed
EP-1767539-A1 ORGANIC ANTIMONY COMPOUND, PROCESS FOR PRODUCING THE SAME, LIVING RADICAL POLYMERIZATION INITIATOR, PROCESS FOR PRODUCING POLYMER USING THE SAME, AND POLYMER OTSUKA CHEMICAL COMPANY, LTD. (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090299008-A1 Organic antimony compound, process for producing the same, living radical polymerization initiator, process for producing polymer using the same, and polymer AOC2, ODC1, MCM7 HDAC3 1896/4885HDAC4 2635/4885HDAC1 766/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.