SCHEMBL680420

SCHEMBL680420

C=CCC(C=O)C(=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29953144 0.82
SCHEMBL29957191 0.82
SCHEMBL471837 0.82
SCHEMBL7219670 0.81 GRIK1 (0.35)
SCHEMBL6822363 0.80
SCHEMBL18191051 0.78
SCHEMBL9790322 0.76 GRIK1 (0.31)
SCHEMBL3737342 0.75 GRIK1 (0.38)
SCHEMBL3737344 0.75 GRIK1 (0.38)
SCHEMBL6024479 0.75 GRIK1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4315910-A IMPROVED STORAGE STABILITY AND SOLUBILITY BY USE OF VINYL ACETATE POLYMERS OR CARBOXYLATED UNSATURATED POLYMERS NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1982-02-16 US claimed
CN-104478844-B The method for preparing ketal and acetal GF 生物化学知识产权资产有限公司 2018-12-04 CN disclosed
EP-2365969-B1 Novel anti-biofilm agents YISSUM RES DEV CO (IL) 2017-03-22 EP disclosed
CN-102939347-B Dispersant and the ketals ester of slipping agent, Preparation Method And The Use as granular solids 赛格提斯公司 2016-08-03 CN disclosed
CN-103890030-B Active polymer filter comprising a pendant dioxirane EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-04-06 CN disclosed
CN-101896474-B Process for the preparation of ketals and acetals Xikaidis Co.,Ltd. (US) 2016-02-03 CN disclosed
CN-104478844-A Method of making ketals and acetals SEGETIS INC 2015-04-01 CN disclosed
US-8865909-B2 Anti-biofilm agents YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2014-10-21 US disclosed
CN-103890030-A Active polymer filter comprising a pendant dioxirane EMPIRE TECHNOLOGY DEV LLC 2014-06-25 CN disclosed
CN-101883773-B Polyketal compounds, synthesis, and applications SEGETIS INC 2014-05-21 CN disclosed
US-6646135-B1 Alpha ketoesters and alpha ketolactones to produce an alpha hydroxy carbonyl compound. ROCHE VITAMINS INC. 2003-11-11 US disclosed
EP-1063224-B1 Continuous hydrogenation process HOFFMANN LA ROCHE (CH) 2003-06-25 EP disclosed
EP-1063224-A1 Continuous hydrogenation process F. HOFFMANN-LA ROCHE AG (CH) 2000-12-27 EP disclosed
US-5166377-A Thromboxane A2 antagonist as coagulants or vasoconstrictors IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-11-24 US disclosed
US-4745198-A CARDIOVASCULAR DISORDERS, BRONCHODILATOR AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-05-17 US disclosed
EP-0094239-B1 1,3-DIOXAN-5-YLALKENOIC ACIDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-07-15 EP disclosed
US-4567197-A THORMBOXANE A2 ANTAGONISTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-28 US disclosed
EP-0094239-A2 1,3-Dioxan-5-ylalkenoic acids IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-11-16 EP disclosed
US-4315910-A IMPROVED STORAGE STABILITY AND SOLUBILITY BY USE OF VINYL ACETATE POLYMERS OR CARBOXYLATED UNSATURATED POLYMERS NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1982-02-16 US disclosed
US-4192861-A Hydrocarbon propelled aerosol hair spray compositions NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-03-11 US disclosed