Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 3/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 3/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | OXTR | P30559 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6662998 | 0.92 | EIF2AK3 (0.42) | EIF2AK3RIPK1CREBBPMAPTKMT2A | |
| SCHEMBL6803357 | 0.91 | EIF2AK3 (0.46) | EIF2AK3RIPK1CREBBPMAPTNPC1 | |
| Hydrochloric Acid SCHEMBL6804708 | 0.91 | EIF2AK3 (0.45) | EIF2AK3RIPK1CREBBPMAPTNPC1 | |
| SCHEMBL6803323 | 0.90 | EIF2AK3 (0.43) | EIF2AK3RIPK1CREBBPMAPTKMT2A | |
| SCHEMBL6804796 | 0.89 | GAA (0.46) | EIF2AK3RIPK1CREBBPMAPTKMT2A | |
| SCHEMBL6800625 | 0.89 | EIF2AK3 (0.43) | EIF2AK3RIPK1CREBBPMAPTHTR2C | |
| SCHEMBL6805404 | 0.88 | EIF2AK3 (0.49) | EIF2AK3RIPK1CREBBPMAPTKMT2A | |
| SCHEMBL6806327 | 0.88 | EIF2AK3 (0.41) | EIF2AK3RIPK1CREBBPMAPTKMT2A | |
| SCHEMBL6667700 | 0.88 | SMO (0.49) | EIF2AK3RIPK1MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL6805924 | 0.87 | SMO (0.49) | EIF2AK3RIPK1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | EIF2AK3 2638/4885RIPK1 3523/4885CREBBP 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.