Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 2/20 | 0.50 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 4/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | EIF2AK1 | Q9BQI3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809248 | 0.93 | SMO (0.56) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| SCHEMBL6668503 | 0.92 | EIF2AK3 (0.51) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| SCHEMBL6803784 | 0.92 | EIF2AK3 (0.53) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| SCHEMBL6804049 | 0.92 | SMO (0.50) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| SCHEMBL6804640 | 0.92 | SMO (0.50) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| SCHEMBL6667301 | 0.91 | SMO (0.51) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL6664580 | 0.91 | EIF2AK3 (0.50) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| SCHEMBL6665157 | 0.91 | SMO (0.49) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| SCHEMBL6804490 | 0.91 | EIF2AK3 (0.50) | SMOEIF2AK3CREBBPHTR2CHTR2B | |
| SCHEMBL6799240 | 0.90 | EIF2AK3 (0.49) | SMOEIF2AK3CREBBPHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | SMO 4390/4885EIF2AK3 2638/4885CREBBP 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.