Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPTLC1 | O15269 | 1/20 | 0.73 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.73 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 4/20 | 0.43 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | CPA1 | P15085 | 3/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12641489 | 1.00 | SPTLC1 (0.73) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL14190631 | 0.98 | SPTLC1 (0.70) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL14190626 | 0.95 | SPTLC1 (0.74) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL6748229 | 0.92 | SPTLC1 (0.74) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL14190634 | 0.91 | SPTLC1 (0.65) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL6748282 | 0.91 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL10082711 | 0.91 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL6802874 | 0.91 | SPTLC1 (0.76) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL31618543 | 0.91 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHACEMME | |
| SCHEMBL6804868 | 0.90 | SPTLC1 (0.75) | SPTLC1SPTLC2FAAHACEMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183005-B1 | Pharmaceutical agents for treating HCV infections | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2012-05-22 | — | — | US | disclosed |
| US-7378446-B2 | Compound having anti-HCV activity and process for producing the same | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-05-27 | — | — | US | disclosed |
| US-7378446-B2 | Compound having anti-HCV activity and process for producing the same | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2008-05-27 | — | — | US | disclosed |