SCHEMBL6804683

SCHEMBL6804683

CCN(C(C)=O)C(=O)C1CCCCN1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 1/20 0.39
PRCP P42785 2/20 0.38
GLI1 P08151 1/20 0.34
DPP7 Q9UHL4 1/20 0.34
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
FDPS P14324 2/20 0.33
NOS2 P35228 2/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4153806 0.81 SCN4A (0.42) SCN4APRCPGLI1DPP7FDPS
SCHEMBL7746794 0.78 SCN4A (0.40) SCN4APRCPGLI1DPP7NOS2
SCHEMBL3632516 0.75 SCN4A (0.46) SCN4APRCPGLI1DPP7NOS2
SCHEMBL5048080 0.75 SCN4A (0.46) SCN4APRCPGLI1DPP7NOS2
SCHEMBL2917600 0.74 GLI1 (0.58) SCN4APRCPGLI1DPP7FDPS
SCHEMBL10067946 0.74 PRCP (0.44) SCN4APRCPDPP7HTR2CHTR2B
SCHEMBL3832254 0.74 GLI1 (0.58) SCN4APRCPGLI1DPP7FDPS
SCHEMBL8285912 0.74 PRCP (0.44) SCN4APRCPDPP7HTR2CHTR2B
SCHEMBL10067945 0.74 PRCP (0.44) SCN4APRCPDPP7HTR2CHTR2B
SCHEMBL16992331 0.74 GLI1 (0.58) SCN4APRCPGLI1DPP7FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040063701-A1 Piperidine derivatives and anti-platelet agents containing the same AJINOMOTO CO., INC (JP) 2004-04-01 US claimed
US-20020147195-A1 Piperidine derivatives and anti-platelet agents containing the same AJINOMOTO CO., INC. (JP) 2002-10-10 US claimed
US-20020019533-A1 PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME MAKINO SHINGO (JP) 2002-02-14 US claimed
EP-0682015-B1 Piperidine derivates and anti-platelet agents containing the same AJINOMOTO KK (JP) 2001-08-22 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019533-A1 PIPERIDINE DERIVATIVES AND ANTI-PLATELET AGENTS CONTAINING THE SAME HTR2A, PDGFRA, PDGFRB SCN4A 2069/4885PRCP 1438/4885GLI1 3203/4885
US-20020147195-A1 Piperidine derivatives and anti-platelet agents containing the same HTR2A, PDGFRA, PDGFRB SCN4A 2069/4885PRCP 1438/4885GLI1 3203/4885
US-20040063701-A1 Piperidine derivatives and anti-platelet agents containing the same HTR2A, PDGFRA, PDGFRB SCN4A 2069/4885PRCP 1438/4885GLI1 3203/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.