Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 9/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804791 | 0.88 | CNR2 (0.38) | CNR2PTGDR2CNR1CYP2C9PSEN1 | |
| SCHEMBL6804793 | 0.82 | ADRB3 (0.35) | CNR2PTGDR2TAS2R14PSEN1PSEN2 | |
| SCHEMBL6683518 | 0.74 | ADRB3 (0.46) | CYP2C9ADRB2ADRB3 | |
| SCHEMBL6683514 | 0.74 | ADRB3 (0.46) | CYP2C9ADRB2ADRB3 | |
| SCHEMBL6681061 | 0.73 | PSEN1 (0.40) | CYP2C9TAS2R14PSEN1PSEN2APH1B | |
| SCHEMBL6681059 | 0.73 | PSEN1 (0.40) | CYP2C9TAS2R14PSEN1PSEN2APH1B | |
| SCHEMBL6682179 | 0.73 | CNR2 (0.41) | CNR2PTGDR2CNR1CYP2C9ADRB2 | |
| SCHEMBL6540726 | 0.72 | L3MBTL1 (0.43) | TAS2R14PSEN1PSEN2SPPL2AAPH1B | |
| SCHEMBL6806070 | 0.72 | MEN1 (0.41) | CYP2C9GAAADRB2ADRB3 | |
| SCHEMBL6805436 | 0.72 | ADRB3 (0.38) | TAS2R14ADRB2ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106653-A1 | Aminoalcohol derivatives | FANCD2, FANCI, HRH2 | CNR2 73/4885PTGDR2 697/4885CNR1 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.