Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | CASP2 | P42575 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 2/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 6/20 | 0.42 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803455 | 0.92 | MAPT (0.44) | CASP3CASP2MAPTNPC1RAB9A | |
| SCHEMBL6804506 | 0.92 | MTTP (0.48) | CASP3CASP2TP53LMNAKDM4E | |
| SCHEMBL6801575 | 0.91 | MAPT (0.53) | CASP3CASP2MAPTNPC1RAB9A | |
| SCHEMBL6800199 | 0.90 | MAPT (0.44) | CASP3CASP2MAPTNPC1RAB9A | |
| SCHEMBL6798990 | 0.89 | MAPT (0.43) | CASP3CASP2MAPTNPC1RAB9A | |
| SCHEMBL6804945 | 0.87 | MAPT (0.46) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6668503 | 0.86 | EIF2AK3 (0.51) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL6803357 | 0.85 | EIF2AK3 (0.46) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6664580 | 0.85 | EIF2AK3 (0.50) | MAPTNPC1RAB9ASMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL6804708 | 0.85 | EIF2AK3 (0.45) | MAPTNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | CASP3 3603/4885CASP2 2284/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.