Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.64 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.64 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.64 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.61 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.61 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.57 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322070 | 0.88 | PARP15 (0.78) | PARP10PARP15PARP2CA1CA2 | |
| Hydrochloric Acid SCHEMBL406803 | 0.86 | PARP15 (0.75) | PARP10PARP15PARP2CA1CA2 | |
| SCHEMBL9018808 | 0.85 | SAE1 (0.61) | SAE1UBA2CA1CA2GSK3B | |
| SCHEMBL7134591 | 0.84 | PLA2G10 (0.83) | PARP10PARP15PARP2PLA2G10PLA2G2A | |
| SCHEMBL580582 | 0.81 | PARP15 (0.48) | PARP10PARP15PARP2PLA2G10PLA2G2A | |
| SCHEMBL1344068 | 0.79 | LOXL2 (0.65) | SAE1UBA2CA2LOXL2IDO1 | |
| SCHEMBL28578951 | 0.79 | PARP15 (0.66) | PARP10PARP15PARP2CA1CA2 | |
| SCHEMBL28950907 | 0.79 | PARP10 (0.66) | PARP10PARP15PARP2CA1CA2 | |
| SCHEMBL6629777 | 0.78 | PARP10 (1.00) | PARP10PARP15PARP2CA1CA2 | |
| SCHEMBL11819138 | 0.77 | PLA2G10 (0.61) | PARP10PARP15PARP2PLA2G10PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | claimed |
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | AJINOMOTO CO. INC | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002521-A1 | Cyclopropanecarboxylic acid amide compound and pharmaceutical use thereof | NFKBIA, IKBKB, CHUK | PARP10 2792/4885PARP15 1220/4885PARP2 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.